The typical silymarin dosage used in most studies was ~420 mg/day divided into 2 or 3 doses. It may be unsafe for your child. Brief stomach upset and mild allergies, but no serious side effects, have been reported. References. Subjects received 140 mg silymarin three times a day for 41 months. The reduced death rate among those taking silymarin was most pronounced in the alcoholic cirrhosis subgroup. Phytosome technology improves the bioavailability of silybin as it is complexed with phosphatidylcholine. MIMS products are highly valued and utilised widely across Australia by healthcare professionals in public and private acute care, primary care, aged care, community services – just to name a few. Search drug, interactions and image information in China, Hong Kong, Taiwan, Malaysia, Singapore, Philippines, Vietnam, Thailand, Indonesia, India & USA 140mg-capsule: 1 capsule/time x 3 times a day. In people with liver disease, the typical dosage was higher, around 1.3 g/day of the standardized for 6 – 8 weeks (divided into 3 doses during the day). Beneficial in a number of diseases involving liver disease; Direction for use/Dosage: – Take as directed by the physician The silymarin exerts membrane-stabilizing and antioxidant activity, it promotes hepatocyte regeneration; furthermore it reduces the inflammatory reaction, and inhibits the fibrogenesis in the liver. A 30-day study in rats found no toxicity at 150 mg/kg/day. In dogs given oral citicoline 1.5 g/kg daily for 6 months, no biochemical, neurological, or histological toxicity was found.1. Common side effects of Silymarin : Abdominal bloating, diarrhea, flatulence, loss of appetite, nausea and stomach upset. Schauss AG, Somfai-Relle S, Financsek I, et al. How should Silymarin be used: It comes as a tablet, capsule, and syrup to take by mouth, with food. Generic Name : Silymarin Pronunciation : SILL-ee-MAR-inn Latest prescription information about Silymarin. The combination of silybin and phosphatidylcholine in Liverprime is three times better absorbed than plain Silymarin. The IV median lethal dose in rodents was suggested to be around 4 g/kg. What is the dose of Legalon® (Silymarin) for a child? 70mg-capsule: 2 capsule/time x 3 times a day. Silymarin is a fruit extract from the plant milk thistle that is claimed to be a free radical scavenger and to have hepatoprotectant properties; it has been used in various liver … 140 Tablet:Role of Silymarin- Powerful antioxidant; Used to protect liver cells (and other cells in the body and brain) from toxins. Click here for full details on all the markets covered. Silymarin may intensify the effects of drugs that decrease blood sugar levels (hypoglycemic drugs). 1. The four-year survival rate was 58 percent in the silymarin group and 39 percent in the placebo group. 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